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Texas A&M University
Mathematics

Events for 10/08/2018 from all calendars

Number Theory Seminar

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Time: 3:00PM - 4:00PM

Location: BLOC 624

Speaker: Guchao Zeng, Texas A&M University at Qatar

Title: v-adic limits of Bernoulli-Carlitz numbers

Abstract: The Bernoulli-Carlitz numbers BC_m for the rational function field K over a finite field of order q do not behave the same as the classical Bernoulli numbers. We show that BC_m has v-adic limits (v is a finite place of K of degree d) for m of the form aq^{dj}+b, where a and b are positive integers. Moreover, the limit is in a constant field extension of K and invariant under the permutation of distance d. Joint work with M. Papanikolas.

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Committee P&T Meeting

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Time: 4:00PM - 5:00PM

Location: BLOC 220

Description: Promotion and tenure discussions.


Industrial and Applied Math

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Time: 4:00PM - 5:00PM

Location: BLOC 117

Speaker: Jonathan Tyler, Texas A&M

Title: Mathematical Modeling in the Pharmaceuticals

Abstract: Mathematical models are used in each step of the drug discovery process to expedite and optimize drug development. Currently, the TransQST (Translational Quantitative Systems Toxicology) consortium is facilitating one such effort to develop open source quantitative systems toxicology (QST) models of four organ systems: GI-immune, heart, kidney, and liver. In this talk, I will give a brief introduction to how math models are used in the drug development process. I will then talk about my summer internship project with Boehringer Ingelheim to make the current TransQST GI-immune model more precise and practical through the addition of key immune species such as cytokines and Th2 cells. Finally, I will present three simulations that address pharmacological issues: (1) Simulation of a Crohn’s patient taking a TNF-alpha inhibitor to address the drug's immunosuppressive action, (2) Sensitivity analysis to help guide in vivo and in vitro experiments, and (3) Generation of virtual parameter sets to address drug efficacy across a population.