Polytopes and Polynomial Systems Frank Sottile 13 February 2006 The exponent of a monomial involving n variables is an integer vector in Z^n. The set of exponents in a polynomial in n variables is its support, and their convex hull is its Newton polytope. Many questions and answers concerning zeroes of multivariate polynomials are best expressed in terms of the discrete structures of support and Newton polytope. The same is true for algorithms and constructions involving multivariate polynomials. In this talk for a general audience from discrete mathematics, I will explain some of this relation between polynomials and polytopes, and give examples of how these structures are used to answer questions involving zeroes of multivariate polynomials.