The Secant conjecture in the real Schubert calculus The story of the deeply surprising proof and consequences of the recent theorem of Mukhin, Tarasov, and Varchenko (n\'ee the Shapiro Conjecture) will be the subject of an address in this year's AMS Current Events Bulletin. The interest in that conjecture was due in no small part to massive computational evidence that was amassed in its study, as the conjecture was originally considered too strong to possibly be true. The Shapiro conjecture as it was originally stated is false for flag manifolds, but experimentation and theory have led to what should be considered as the `correct' form for flag manifolds. A proof of this generalization for certain two-step flag mainfolds by Eremenko, Gabrielov, Shapiro, and Vainshtein led to another generalization, which we call the Secant conjecture. In this talk, I will explain some of this history, state the Secant Conjecture, and describe some of the massive computational evidence (involving hundreds of Gigahertz-years of computation) in its favor.