Towards a multivariate Descartes' Rule The gold standard in understanding the real solutions to systems of equations is Descartes' rule of signs (c. 1637), which bounds the number of positive zeroes of a univariate polynomial by the number of changes in the signs of its coefficients. Ignoring signs, a univariate polynomial with d+2 terms has at most d+1 positive zeroes. For multivariate polynomials, the situation is not settled. In 1980 Khovanskii gave a version of this second estimate, which was refined a decade ago, but is considered to be far from sharp. Recently, there have been several results giving bounds related to signs of coefficients that may suggest aspects of an eventual multivariate Descartes' rule. My talk will discuss the history and these recent results.